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. 2005 Oct 11;102(42):15110–15115. doi: 10.1073/pnas.0504407102

Fig. 4.

Fig. 4.

Confinement of VLPs on the cell surface does not require caveolae or clathrin-coated pits. TIRF images of AF568 VLPs bound to the bottom surface of live 3T6 cells expressing clathrin light chain–GFP (a) or caveolin-1–GFP (b). (Scale bars, 10 μm.) For each construct, a representative merged, dual-color image of a whole cell (Upper) and close-ups (insets in Upper shown in Lower) are shown. (c) D/SMSS plot of VLP trajectories from particles bound to lung fibroblasts obtained from caveolin-1 knockout mice.