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. 2005 Oct 3;102(42):15167–15172. doi: 10.1073/pnas.0504981102

Fig. 1.

Fig. 1.

Telomere fusions in various mutants. DAPI-stained mitotic nuclei from third instar larval neuroblasts. (A) A WT female nucleus with all of the chromosomes labeled. (B)A grp1 tefu nucleus. Two fusions between chromosomes 2 and 4 (arrow) are defined as a double fusion. The two chromosome 4s are fused, which is defined as an other fusion because one cannot unequivocally define it as either single or double fusion. An unknown fragment (indicated by?) is fused with the short arm of an X chromosome (arrowhead). (C)A Su(var)2–504/05 tefu nucleus. A single fusion between the two sisters of an X chromosome is indicated by an arrowhead. Five double fusions (X-2, 3–3, 3–2, 2–4, and between the short and long arms of an X) are also present. (D) A mus304D1/D3 tefu nucleus. Fusions present are: five single nonsister fusions (arrows), a double X-2 fusion, and an other fusion between a 4 and the short arm of an X. (E)A mei-4129D tefu nucleus. Fusions present are: several double fusions (arrows) forming two chromosome “chains,” an intra-Y fusion (the ring), and two sister fusions (arrowheads). Note that one arm of chromosome 3 is longer than the same arm from its homolog indicative of a rearrangement. (F)A cav1 nucleus. Fusions present are: two 2–3, two X-4, and one intra-3 (the ring) double fusions and two X-4 other fusions. (G) A mei-41RT1 nbs1 nucleus. Fusions present are: two 2–2 (the ring) and one 3–3 double fusions, an X sister (arrowhead), and one 3–3 (arrow) single fusion. (H)A mei-41RT1 tefu nucleus. Double fusions among chromosomes 2 and 3 led to chromosome entanglement (arrowhead). The two Xs are entangled (arrow) accompanied by two sister fusions. (I) A mei-4129D mre11 nucleus showing numerous chromosome fragments. (J) A mus304D1/D3 tefu nucleus in anaphase with seven bridges between the two separating nuclei (arrow). (K) A mei-4129D tefu polyploid nucleus with all chromosome ends fused. (L) A tetraploid mei-41RT1 tefu nucleus. The four chromosome 2s formed a cluster by multiple fusions. The four 3s and the two Ys are clustered by multiple fusions. The two Xs and two 4s formed a ring structure.