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The structure of a V3-loop peptide in the binding site of the antibody 447 (38). The CDRH3 loop (pink, numbered) forms a mixed β-sheet with the V3 loop (blue). GPGR forms the turn in the peptide structure and interacts with the base of the CDRH3 loop. Main-chain interactions dominate the interaction of the peptide with the CDRH3 loop.
