. 2025 Oct 31;25:536. doi: 10.1186/s12871-025-03416-0

Table 2.

Analysis of the success rate performed using probit regression

Drug	ED₅₀, mg/kg	95% CIs	ED₉₅, mg/kg	95% CIs	Median Potency Ratio
Ciprofol	0.35	0.33–0.38	0.53	0.48–0.60	Propofol: Ciprofol 4.1 (2.4- 9.0)
Propofol	1.44	1.32–1.56	2.16	1.96–2.45

Drug

ED₅₀,
mg/kg

95% CIs

ED₉₅,
mg/kg

95% CIs

Median Potency Ratio

Ciprofol

0.35

0.33–0.38

0.53

0.48–0.60

Propofol: Ciprofol

4.1

(2.4- 9.0)

Propofol

1.44

1.32–1.56

2.16

1.96–2.45

results of the success rate performed using probit regression showed, Ciprofol : Probit(p)=4.253+9.407× logdose, Propofol:Probit(p)=-1.498+9.407× log_dose (P=0.620>0.05)

Abbreviations: ED95, dose giving a 95% response, 95% CIs, 95% confidence intervals