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. 2025 Oct 27;17:2441–2457. doi: 10.2147/CMAR.S540752

Figure 4.

Figure 4

Serum tRF5-23-GlyTCC-2 combined with CEA enhances the adjunctive diagnosis of CRC. (A) ROC curves comparing the ability of tRF5-23-GlyTCC-2 and CEA to discriminate between colorectal cancer (CRC) patients (n=122) and healthy donors (n=120). (B) ROC curves comparing the ability of tRF5-23-GlyTCC-2, CEA, and their combination to discriminate between colorectal cancer (CRC) patients (n=122) and healthy donors (n=120). (C) ROC curves comparing the ability of tRF5-23-GlyTCC-2 and CEA to discriminate between CRC patients (n=122) and patients with colon polyps (n=71). (D) ROC curves comparing the ability of tRF5-23-GlyTCC-2, CEA, and their combination to discriminate between CRC patients (n=122) and patients with colon polyps (n=71).