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. 2025 Oct 27;17:2441–2457. doi: 10.2147/CMAR.S540752

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© 2025 Lv et al.

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tRF5-23-GlyTCC-2 exhibits anti-cancer effects both in vivo and in vitro. (A) The impact of transfection with tRF5-23-GlyTCC-2 inhibitors and mimics on the proliferation of SW116, HCT116, and DLD1 cells was assessed through a cell colony formation experiment. (B) Animal experiment workflow diagram. (C and D) Establishment of CRC cell line xenograft tumor model in nude mice. (E) Tumor tissue weight in nude mice. (F) Tumor volume growth curve in nude mice.