Figure 3.

ANLN mRNA and protein expression analysis for pancreatic adenocarcinoma tissues from TCGA and CPTAC databases using the UALCAN platform. (A) The boxplots were downloaded from the UALCAN based on TCGA PAAD dataset. The left box represents ANLN mRNA expression in normal pancreatic tissues (n=4), wherein the right box represents ANLN mRNA expression in pancreatic adenocarcinoma tissues (n=178) (p<1E-12). p<0.05 was regarded as statistically significant. (B) The boxplots were downloaded from UALCAN based on CPTAC PAAD dataset. The left box represents ANLN protein expression in normal pancreatic tissues (n=74), wherein the right box represents ANLN protein expression in pancreatic adenocarcinoma tissues (n=137) (p=4.26941959587804E-172). p<0.05 was regarded as statistically significant. ANLN: Anillin actin-binding protein; CPTAC: Clinical Proteomic Tumor Analysis Consortium; TCGA: The Cancer Genome Atlas; GEPIA: Gene Expression Profiling Interactive Analysis; PAAD: pancreatic adenocarcinoma; UALCAN: University of Alabama at Birmingham Cancer Data Analytics Portal.