Fig. 7. Anandamide blocks α_1I currents during thalamic relay cell-like activities. A firing activity typical of those of thalamic relay neurons was used as waveform (upper panel), and the resulting α_1I currents are presented in the absence [ctrl (a)] and presence of increasing concentrations of anandamide [10 nM (b), 100 nM (c) and 1 µM (d)]. The normalized integral of total current (arbitrary units) is shown as an inset (n = 6).