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. 2025 Oct 31;25(1):338. doi: 10.1007/s10238-025-01800-1

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© The Author(s) 2025

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 6 — The characteristic of immune infiltration and drug sensitivity based on the risk model. A-K. The correlation analysis between immune cells and the PANoptosis-related risk score. L. The correlation analysis between immune cells and twelve PANoptosis-based regulators. M. The correlation analysis between ESTIMATE scores and the PANoptosis-related risk score. N. The tumor stemness correlation analysis shows the relationship between the PANoptosis-related risk score and stemness scores. O-R. The relationship between sensitivity to therapeutic drugs and risk score. *. p < 0.05; **. p < 0.01; ***. p < 0.001