Fig. 3.

Geometric LSM ratios (90% CI) of C_max, AUC_0–∞, and AUC_0–tlast for mirikizumab a 200 mg and b 300 mg delivered in the abdomen, arm, or thigh by AI versus PFS. The devices were considered bioequivalent if the 90% CI of the ratio of geometric LSM fell within 0.80 to 1.25. AI autoinjector, AUC_0–∞ area under the concentration versus time curve from time zero to infinity, AUC_0–tlast area under the concentration versus time curve from time zero to time t, where t is the last time point with a measurable concentration, CI confidence interval, C_max maximum observed drug concentration, LSM least squares mean, PFS prefilled syringe