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. 2025 Sep 3;42(11):5529–5546. doi: 10.1007/s12325-025-03335-z

Table 4.

Treatment-emergent adverse events following mirikizumab administered with either prefilled syringe or autoinjector

Participants with event, n (%) Study AMBW (mirikizumab 200 mg) Study AMBX (mirikizumab 300 mg)
PFS (N = 120) Autoinjector (N = 120) PFS (N = 117) Autoinjector (N = 120)
All TEAEs 43 (35.8) 39 (32.5) 39 (33.3) 45 (37.5)
Treatment-related TEAEs 18 (15.0) 21 (17.5) 12 (10.3) 15 (12.5)
Device-related TEAEs 8 (6.7) 11 (9.2) 2 (1.7) 11 (9.2)
SAEs 0 0 0 1 (0.8)
Deaths 0 0 0 0
AEs leading to study discontinuation 0 0 2 (1.7) 0
Infection TEAEs 7 (5.8) 11 (9.2) 10 (8.5) 13 (10.8)
Systemic allergic/hypersensitivity TEAEs 0 0 0 0

AE adverse event, PFS prefilled syringe, SAE serious adverse event, TEAE treatment-emergent adverse event