Table 1. Literature search strategy across selected electronic databases.

This table summarizes the databases searched, key concepts/keywords used, detailed search strategies, applied filters (timeframe: last 15 years), and the number of records retrieved for studies related to Slo2 channels, KCNT1/KCNT2, and associated neurodevelopmental disorders including intellectual disability.

PMC: PubMed Central, DOAJ: Directory of Open Access Journals.

Databases	Keywords	Search strategy	Filters	Search result
PubMed	Slo2 channels and intellectual disability, developmental delay	(KCNT1 OR "Slo2" OR "Slack channel" OR "Sodium-activated potassium channel")  AND ("intellectual disability" OR "mental retardation" OR "cognitive impairment" OR "developmental delay")	Last 15 years	48
Google Scholar	Slo2 channels and intellectual disability	FMRP AND KCNT1 AND "intellectual disability"	Last 15 years	143
Semantic Scholar	Slo2 channels and intellectual disability, cognitive impairment	"KCNT1 intellectual disability", "Slack channel cognitive impairment", "Potassium channel neurodevelopmental disorder"	Last 15 years	34
Europe PMC	Slo2 channels and intellectual disability	(KCNT1 OR "Slo2" OR "Slack channel" OR "Sodium-activated potassium channel")  AND ("intellectual disability" OR "mental retardation" OR "cognitive impairment" OR "developmental delay")  NOT epilepsy	Last 15 years	73
DOAJ	Slo2 channel	Slo2 channel	Last 15 years	3