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(A) CD spectra for the pyrene-modified RNA oligonucleotide duplex, I/VIII (bold line) and unmodified RNA duplex, VI/VIII (thin line). (B) CD spectra for pyrene-modified DNA oligonucleotide duplex, II/IX (bold line) and unmodified DNA duplex, VII/IX (thin line). Measurements were carried out at room temperature for a 1:1 mixture of oligonucleotides (6 µM) in a pH 7 buffer containing 10 mM sodium phosphate and 100 mM NaCl.
