Table 1.

A summary of the detection of RREO events in EST and mRNA sequences from six species

	Human	Mouse	Rat	Chicken	Zebrafish	Fruit fly
Number of EST sequences in GenBank	6 057 800	4 334 174	701 039	540 881	630 156	383 407
Number of mRNA sequences in GenBank	194 508	172 159	17 575	26 296	13 064	15 897
No. of EST sequences confirming non-linear single exon splicing	25 (Supplementary Table A)a	28 (Supplementary Table E)a	2 (Supplementary Table I)a	0	3 (Supplementary Table N)a	6 (Supplementary Table Q)a
No. of mRNA sequences confirming non-linear single exon splicing	3 (Supplementary Table B)a	9 (Supplementary Table F)a	0	1 (Supplementary Table K)a	1 (Supplementary Table O)a	1 (Supplementary Table R)a
No. of EST sequences confirming non-linear multi-exon splicing	221 (Supplementary Table C)a	48 (Supplementary Table G)a	15 (Supplementary Table J)a	9 (Supplementary Table L)a	23 (Supplementary Table P)a	1 (Supplementary Table S)a
No. of mRNA sequences confirming non-linear multi-exon splicing	14 (Supplementary Table D)a	13 (Supplementary Table H)a	0	2 (Supplementary Table M)a	0	0
Total no. of expressed sequences confirming non-linear splicing	263	98	17	12	27	8
Total no. of genes involved in non-linear splicing	178	61	7	6	8	5

^aEach supplementary table contains the EST or mRNA GenBank ID, Ensembl exon and gene identifiers as well as the sequence of the 100 bp non-linear splice sequence used to detect each event.