Table 1.

Ligand binding site prediction comparison with Pei et al. (11)

PDB code	Apo PDB	Number of ASZa within the top 25% conservation difference in Pei et al. (17)	Number of ASZ within the top 25% our score
8pca	2ctn	11	13
2a8v	1a8v	6	8
1btz	2ptn	12	12
1rge	1rgg	6	7
148l	5lzm	11	13

^aThe active site zone (ASZ) is defined as all the residues within 4.5 Å of the binding ligand.