Table 1:

Regulation patterns of AC-isoforms [17].

	G proteins
AC-isoforms	Stimulation	Inhibition
Group I
AC1	${\mathrm{G}}_{{\alpha }_s}$	${\mathrm{G}}_{\beta \gamma }$, ${\mathrm{G}}_{{\alpha }_i}$, ${\mathrm{G}}_{{\alpha }_z}$, ${\mathrm{G}}_{{\alpha }_o}$
AC8	${\mathrm{G}}_{{\alpha }_s}$	${\mathrm{G}}_{\beta \gamma }$
AC3	${\mathrm{G}}_{{\alpha }_s}$	${\mathrm{G}}_{\beta \gamma }$
Group II
AC2	${\mathrm{G}}_{{\alpha }_s}$, ${\mathrm{G}}_{\beta \gamma }$
AC4	${\mathrm{G}}_{{\alpha }_s}$, ${\mathrm{G}}_{\beta \gamma }$
AC7	${\mathrm{G}}_{{\alpha }_s}$, ${\mathrm{G}}_{\beta \gamma }$
Group III
AC5	${\mathrm{G}}_{{\alpha }_s}$, ${\mathrm{G}}_{\beta \gamma }$	${\mathrm{G}}_{{\alpha }_i}$, ${\mathrm{G}}_{{\alpha }_z}$
AC6	${\mathrm{G}}_{{\alpha }_s}$, ${\mathrm{G}}_{\beta \gamma }$	${\mathrm{G}}_{{\alpha }_i}$, ${\mathrm{G}}_{{\alpha }_z}$
Group IV
AC9	${\mathrm{G}}_{{\alpha }_s}$