Table 5:

Parameter values for cAMP production

symb.	parameter	value	reference
$k_w$	active cAMP production rate	6.713s−1	[9] (modif. for AC6)
$K_{as}$	dissociat. const for AC6 and $G_{{\alpha }_s}$	0.2μM	[34]
$K_{ai}$	dissociat. const for AC6 and $G_{{\alpha }_i}$	0.027μM	[34]
$d_w$	cAMP degradation rate by PDE4	8.66s−1	[32]
$K_w$	dissociat. const for PDE4 and cAMP	1.21μM	[32]
$A^{tot}$	total AC concentration	0.0497μM	[6]
$P^{tot}$	total PDE concentration	0.039μM	[6]