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. 2025 Sep 30;13(11):e00559-25. doi: 10.1128/spectrum.00559-25

TABLE 4.

Diagnostic accuracy of SEPSI ID and SEPSI DR panelsa

Measure of diagnostic accuracy % (95% CI)
SEPSI ID blood culture SEPSI DR blood culture resistance
Sensitivity 96.88 (95.58–99.36) 97.8 (92.2–99.7)
Specificity 100 (86.77–100) 89.7 (72.6–97.8)
PPV 100 (96.09–100) 96.7 (90.7–99.3)
NPV 89.66 (73.89–96.42) 92.9 (76.5–99.1)
LHR+ b 9.45 (3.24–27.6)
LHR- 0.03 (0.009–0.108) 0.02 (0.01–0.10)
Accuracy 97.54 (93.78–99.18) 95.8 (90.5–98.6)
F1 score 98.41 97.2
a

CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; LHR+, positive likelihood ratio; LHR−, negative likelihood ratio.

b

The infinite LHR⁺ reflects the absence of false positives (100% specificity), indicating the test’s exceptional ability to confirm the condition when positive.