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. 2025 Nov 4;15(50):42771–42842. doi: 10.1039/d5ra06960b

Table 7. Detection of CIT using a variety of analytical methods along with their LODs.

S. No. Method Analyte Electrode modifier Linear range LOD Sample/recovery Ref.
1 ECL CIT MIP/NCQDs/Ru(bpy)3@SiO2 1.0 × 10−3–1.0 × 10−1 ng mL−1 5.0 × 10−6 ng mL−1 Red rice/95.5–102% 375
Millet/99.2–102%
2 SWV CIT MIP/[APMIm]Br/BN-HPC/GCE 1.0 × 10−2–10 ng mL−1 1.0 × 10−4 ng mL−1 Red yeast rice/98.4–102% 368
Rice/97.3–112%
Wheat/102–107%
3 Cas12a/EXPAR-HCR CIT 0.005–500 μg mL−1 0.127 ng mL−1 Oat/97–104% 373
Flour/105–111%
4 FRET-based immunosensor CIT 1 × 10−12–6 × 10−12 M 1 × 10−13 M Human serum 376 and 377
5 Spectrofluorimetry CIT 0–0.15 μg mL−1 1.0 μg kg−1 Red fermented rice/91.6–95.0% 377
6 UiO66-MOF CIT 0.08–1.00 μM 0.042 μM Wheat and feeds 378
7 DF-ICA CIT 0.06 ng mL−1 Corn/86.3–111.6% 367
8 HPLC-FLD CIT DNA1/MB/p-PtNTs/MCH/TDN-Apt/AuE 0.1–1 × 104 ng mL−1 1.95 × 10−2 ng mL−1 Corn/97.02–99.04% 370
9 ic-ELISA CIT 5.9–230 pg mL−1 0.6 μg mL−1 Wine/intra-assay (84.7–92.0%) and inter-assay (83.6–91.6%) 379
10 HPLC CIT 0.005–50 μg g−1 0.001 μg g−1 Apple and pear/84–101% 380
11 DPV CIT cDNA/MB/PtPdCo MNZs/MCH/TDN-Apt/AuE 0.01–1 × 104 ng mL−1 7.67 × 10−3 ng mL−1 (DPV) Cornmeal/96.98–104.15% (DPV) and 101.17–108.01% (SWV) 369
SWV 1.57 × 10−3 ng mL−1 (SWV) Red yeast rice/96.81–103.84% (DPV) and 102.49–107.22% (SWV)
12 UHPLC-MS/MS CIT 1–1000 μg kg−1 0.07 μg kg−1 Red rice/82–92% 381
RYR/90–104%
13 X27-based real time immune-PCR (rtIPCR) CIT 0.1–1000 ng mL−1 0.08 ng mL−1 Rice flour/90.0–104.6% 382
20 ng mL−1 (in Monascus-rice or Monmascus products) Flour/75.8–110.0%
14 LC-MS/MS CIT 0.14 ng mL−1 (in urine) Urine/94.8–107% 383
0.04 ng mL−1 (in plasma) Plasma/96.2–109%
15 CZE CIT 4.5–150.0 μg kg−1 1.5 μg kg−1 Peper/98% 384
16 UHPLC-HRMS CIT >LOD-4.0 ng mg−1 0.003 ng mL−1 Urine/70–86% 385
17 ciELISA CIT 0.04 ng mL−1 Wheat/87.1–115.6% 386
0.007 ng mL−1 Corn/86.6–107.9
18 RAFTPP-HPLC CIT MIP/NIP 1–100 μg kg−1 0.35 μg kg−1 Rye/98–100.0% 387
19 DPV CIT 0.1- 4.52 × 10−11 g mL−1 374
0.1–10000 ng mL−1
20 HPLC CIT 50–200 μg kg−1 3 μg kg−1 Dark tea/89.87–98.92% 388