TABLE 3.
DNA changes detected in the QRDR, including gyrA, gyrB, parC, and parE genes in fluoroquinolone-resistant MRSA clinical isolatesa
| Strain Gene |
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| gyrA | C251T | C251T | C251T | C251T | C251T | C251T | C251T | C251T | C251T | C251T | C251T | C251T | C251T | C251T | C251T |
| 361delA | A501G | A501G | A501G | 361delA | 391delA | A501G | T253C | T253C | G262A | G451A | T253C | 361delA | T500C | A501G | |
| A501G | T513A | T513A | T513A | A418G | A501G | T513A | A501G | 361delA | A501G | A501G | A501G | C525G | T513A | ||
| T513A | C525A | C525A | C525A | 451delG | T513A | C525A | T513A | 451delG | T513A | T513A | T513A | 543delG | C525A | ||
| C525G | A501G | C525A | C525A | A501G | C525A | C525G | C525A | 543delG | |||||||
| 563delT | T513A | T513A | A570C | ||||||||||||
| C525A | C525G | ||||||||||||||
| T563A | |||||||||||||||
| gyrB | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND | ND |
| parC | ND | C239T | C239T | C239T | C239T | C239T | C239T | C239T | C239T | C239T | C239T | C239T | C239A | C239A | C239T |
| G250A | G250A | G250A | G250A | ||||||||||||
| 608delA | |||||||||||||||
| 612delA | |||||||||||||||
| parE | ND | ND | 1205delA | ND | C1351T | ND | ND | ND | ND | ND | C1351T | ND | ND | ND | ND |
| C1351T |
a
ND, not detected.