Table 1.

Structural statistics for free-state Sox2^31–127

A. Restraint information
Total number of distance restraints	1577
Intra-residual/sequential/medium/long	454/423/455/245
Total number of RDC restraints	43
	97/42/16/0
Total number of backbone dihedral angle restraints f/yq	57/60
B. Average deviation from experimental restraints
RMS experimental distance restraints (Å)	0.0090 ± 0.0010
Average number of distance violations > 0.5 Å	0
RMS experimental dihedral angle restraints (°)	0.249 ± 0.055
Average number of dihedral angle violations > 5°	0
RMS experimental RDC restraints (Hz)	0.79 ± 0.02
RDC Q-factor	8.07 ± 0.21
C. Coordinate RMS deviation (Å)
Average overall RMSD to mean structure  a
Ordered heavy backbone atoms	0.46 ± 0.19
Ordered all heavy atoms	0.86 ± 0.13
Global backbone atoms	9.58 ± 3.81
	1.64
Global all heavy atoms	9.84 ± 3.71
	2.25
D. Ramachandran plot quality parameters (%)  a
Residues in most favored regions (ordered/global)	97.8 / 77.0
	83.0 /± 4.5
Residues in allowed regions (ordered/global)	2.2 / 19.0
	13.5 ± 4.0
Residues in additionally allowed regions (ordered/global)	0.0 / 2.6
	2.3 ± 2.1
Residues in disallowed regions (ordered/global)	0.0 / 1.4
	1.1 ± 1.1
E. Abnormalities found in structural checks
Abnormally short interatomic distances /1000 atoms	4.24
	10 ± 2

^aStatistics are given for residues 31–127. Ordered regions are residues 45–103.