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. 2025 Nov 4;15:38455. doi: 10.1038/s41598-025-91777-4

Table 3.

Conventional, speckle tracking and 3D echocardiography findings in patient and control groups.

Variables Control Before transplant After transplant P* P†
Conventional echo
 LVIDs (mm) 2.5 ± 1.22 2.67 ± 0.80 2.64 ± 0.76 0.622 0.275
 LVIDd (mm) 3.9 ± 0.89 3.84 ± 0.87 3.95 ± 0.81 0.59 0.065
 EF (%) 67 ± 3 67.02 ± 3.30 67.03 ± 5.90 0.57 0.997
 FS (%) 40 ± 4.8 36.99 ± 4.27 35.52 ± 3.92 0.04* 0.029*
Speckle tracking (%)
 GLS Avg − 19.8 ± 1.7 − 18.98 ± 1.82 − 17.34 ± 2.04 0.09 < 0.001*
 Septal LS apex − 16.5 ± 1.8 − 15.44 ± 2.01 − 14.88 ± 1.58 0.06 0.015*
 Septal LS mid − 16.9 ± 1.3 − 16.58 ± 1.72 − 15.90 ± 1.73 0.33 0.005*
 Septal LS base − 21 ± 3.2 − 20.33 ± 3.90 − 19.70 ± 3.88 0.37 0.006*
 Lateral LS apex − 16.5 ± 1.5 − 15.73 ± 1.46 − 14.66 ± 1.52 0.07 < 0.001*
 Lateral LS mid − 19.3 ± 2.6 − 18 ± 3.47 − 16.98 ± 3.02 0.18 0.004*
 Lateral LS base − 31 ± 4.7 − 29.36 ± 5.16 − 27.98 ± 5.40 0.25 < 0.001*
3D ECHO
 EDVI (ml) 70.9 ± 18.5 70.09 ± 18.13 69.22 ± 23.57 0.87 0.767
 ESVI(ml) 27.40 ± 11 26.60 ± 11.12 25.16 ± 9.82 0.80 0.115
 3D EF (%) 70.3 ± 4.6 67.62 ± 3.87 64.74 ± 6.57 0.04* 0.005*
 3D SV (ml) 59.9 ± 9 57.04 ± 9.71 53.34 ± 10.66 0.29 0.002*

Significant values are in [bold].

LVIDs: left ventricular internal dimension at end-systole, LVIDd: left ventricular internal dimension at end-diastole, EF: ejection fraction, FS: fractional shortening, SD: standard deviation, GLS: global longitudinal strain, LS: longitudinal strain, Avg: Average, LVEDV: left ventricular end-diastolic volume, LVESV: left ventricular end-systolic volume, 3D EF: three-dimensional ejection fraction, SV: three-dimensional stroke volume. Data are expressed as mean ± SD*Control group versus patient group before HSCT.†Patients before HSCT versus patients after HSCT. P*: independent sample t-test. P†: paired sample t-test.*significant p ≤ 0.05.