Table 3.
Conventional, speckle tracking and 3D echocardiography findings in patient and control groups.
| Variables | Control | Before transplant | After transplant | P* | P† |
|---|---|---|---|---|---|
| Conventional echo | |||||
| LVIDs (mm) | 2.5 ± 1.22 | 2.67 ± 0.80 | 2.64 ± 0.76 | 0.622 | 0.275 |
| LVIDd (mm) | 3.9 ± 0.89 | 3.84 ± 0.87 | 3.95 ± 0.81 | 0.59 | 0.065 |
| EF (%) | 67 ± 3 | 67.02 ± 3.30 | 67.03 ± 5.90 | 0.57 | 0.997 |
| FS (%) | 40 ± 4.8 | 36.99 ± 4.27 | 35.52 ± 3.92 | 0.04* | 0.029* |
| Speckle tracking (%) | |||||
| GLS Avg | − 19.8 ± 1.7 | − 18.98 ± 1.82 | − 17.34 ± 2.04 | 0.09 | < 0.001* |
| Septal LS apex | − 16.5 ± 1.8 | − 15.44 ± 2.01 | − 14.88 ± 1.58 | 0.06 | 0.015* |
| Septal LS mid | − 16.9 ± 1.3 | − 16.58 ± 1.72 | − 15.90 ± 1.73 | 0.33 | 0.005* |
| Septal LS base | − 21 ± 3.2 | − 20.33 ± 3.90 | − 19.70 ± 3.88 | 0.37 | 0.006* |
| Lateral LS apex | − 16.5 ± 1.5 | − 15.73 ± 1.46 | − 14.66 ± 1.52 | 0.07 | < 0.001* |
| Lateral LS mid | − 19.3 ± 2.6 | − 18 ± 3.47 | − 16.98 ± 3.02 | 0.18 | 0.004* |
| Lateral LS base | − 31 ± 4.7 | − 29.36 ± 5.16 | − 27.98 ± 5.40 | 0.25 | < 0.001* |
| 3D ECHO | |||||
| EDVI (ml) | 70.9 ± 18.5 | 70.09 ± 18.13 | 69.22 ± 23.57 | 0.87 | 0.767 |
| ESVI(ml) | 27.40 ± 11 | 26.60 ± 11.12 | 25.16 ± 9.82 | 0.80 | 0.115 |
| 3D EF (%) | 70.3 ± 4.6 | 67.62 ± 3.87 | 64.74 ± 6.57 | 0.04* | 0.005* |
| 3D SV (ml) | 59.9 ± 9 | 57.04 ± 9.71 | 53.34 ± 10.66 | 0.29 | 0.002* |
Significant values are in [bold].
LVIDs: left ventricular internal dimension at end-systole, LVIDd: left ventricular internal dimension at end-diastole, EF: ejection fraction, FS: fractional shortening, SD: standard deviation, GLS: global longitudinal strain, LS: longitudinal strain, Avg: Average, LVEDV: left ventricular end-diastolic volume, LVESV: left ventricular end-systolic volume, 3D EF: three-dimensional ejection fraction, SV: three-dimensional stroke volume. Data are expressed as mean ± SD*Control group versus patient group before HSCT.†Patients before HSCT versus patients after HSCT. P*: independent sample t-test. P†: paired sample t-test.*significant p ≤ 0.05.