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. 2025 Nov 5;25:1711. doi: 10.1186/s12885-025-14669-w

Table 2.

Different insulin resistance biomarkers in patients with colorectal cancer

Insulin resistance biomarkers Metastatic colorectal cancer Mean ± SD (n = 24) Non-metastatic colorectal cancer Mean ± SD (n = 63) p Value* FDR adjusted p-value
LHR 3.305 ± 1.129 1.892 ± 0.732 < 0.000* 0.0005
TCHR 4.548 ± 0.893 3.272 ± 1.023 < 0.000* 0.00025
TyG 3.548 ± 0.893 2.272 ± 1.023 < 0.000* 0.000167
TGHR 3.960 ± 2.265 2.680 ± 1.351 0.001* 0.00125
AI 8.716 ± 0.486 8.649 ± 0.429 0.399 0.399

*Mann-Whitney test, p < 0.05 is statistically significant

All IR biomarkers except AI remain significant (FDR < 0.05) after Benjamini-Hochberg adjustment