Table 1.
Relationships of Veteran Status with Epigenetic Aging
| Model/measure | Estimate (95% CI) | P-value | n |
|---|---|---|---|
| Minimally-adjusted | |||
| HannumAge (years) | 0.72 (−0.52, 1.96) | .24 | 2344 |
| HorvathAge (years) | 0.62 (−0.44, 1.69) | .24 | 2344 |
| SkinBloodAge (years) | 0.86 (−0.10, 1.81) | .08 | 2344 |
| PhenoAge (years) | 0.37 (−0.88, 1.61) | .55 | 2344 |
| GrimAge2 (years) | 0.71 (−0.07, 1.49) | .07 | 2344 |
| DNAmTL (kb) | −0.01 (−0.05, 0.03) | .53 | 2344 |
| DunedinPoAm | −0.003 (−0.01, 0.01) | .65 | 2344 |
| Imputed fully-adjusted | |||
| HannumAge (years) | 0.86 (−0.41, 2.13) | .15 | 2344 |
| HorvathAge (years) | 0.78 (−0.37, 1.93) | .15 | 2344 |
| SkinBloodAge (years) | 1.00 (−0.01, 2.00) | .05 | 2344 |
| PhenoAge (years) | 0.58 (−0.77, 1.92) | .33 | 2344 |
| GrimAge2 (years) | 0.69 (−0.14, 1.52) | .09 | 2344 |
| DNAmTL (kb) | −0.02 (−0.07, 0.02) | .23 | 2344 |
| DunedinPoAm | −0.005 (−0.02, 0.01) | .32 | 2344 |
| Fully-adjusted complete case sensitivity | |||
| HannumAge (years) | 0.79 (−0.4, 1.98) | .15 | 1829 |
| HorvathAge (years) | 0.79 (−0.29, 1.86) | .12 | 1829 |
| SkinBloodAge (years) | 0.75 (−0.22, 1.71) | .11 | 1829 |
| PhenoAge (years) | 0.62 (−0.64, 1.87) | .27 | 1829 |
| GrimAge2 (years) | 0.64 (−0.33, 1.60) | .16 | 1829 |
| DNAmTL (kb) | −0.02 (−0.07, 0.03) | .30 | 1829 |
| DunedinPoAm | −0.01 (−0.02, 0.004) | .19 | 1829 |
Model estimates are for veterans (nonveterans are the reference group).
Minimally-adjusted model adjustments: chronological age, chronological age2, sex, and race/ethnicity.
Fully-adjusted model adjustments: Minimally-adjusted + alcohol, BMI, education, general health, occupation, physical activity, PIR, smoking, and estimated leukocyte proportions. BMI, body mass index; PIR, poverty-to-income ratio.
P < .05: statistically significant.
P < .10: marginally significant.