Table 2.

Relationships of Veteran Status with GrimAge2 Components

Model/measure	Estimate (95% CI)	P-value	n
Minimally-adjusted
A1c	0.006 (0.0005, 0.01)	.03	2344
ADM	1.14 (−1.14, 3.41)	.31	2344
B2M	12,593.58 (−2628.63, 27,815.78)	.10	2344
CRP	0.06 (−0.01, 0.13)	.08	2344
Cystatin C	3009.40 (−534.21, 6553.01)	.09	2344
GDF15	2.97 (−12.71, 18.65)	.70	2344
Leptin	166.99 (−153.08, 487.05)	.29	2344
Pack-years	0.67 (−1.24, 2.58)	.48	2344
PAI1	46.03 (−378.12, 470.17)	.82	2344
TIMP1	71.14 (8.28, 134.01)	.03	2344
Imputed fully-adjusted
A1c	0.005 (−0.0005, 0.01)	.07	2344
ADM	1.08 (−1.29, 3.45)	.30	2344
B2M	15,351.93 (−2929.33, 33,633.19)	.08	2344
CRP	0.06 (−0.02, 0.14)	.10	2344
Cystatin C	3827.72 (−76.18, 7731.61)	.05	2344
GDF15	4.92 (−17.33, 27.17)	.60	2344
Leptin	136.09 (−266.84, 539.03)	.43	2344
Pack-years	0.15 (−1.72, 2.02)	.85	2344
PAI1	22.73 (−472.09, 517.54)	.91	2344
TIMP1	96.40 (−15.05, 207.85)	.08	2344
Fully-adjusted complete case sensitivity
A1c	0.003 (−0.003, 0.01)	.29	1829
ADM	2.11 (−0.66, 4.88)	.11	1829
B2M	13,593.07 (−6649.6, 33,835.73)	.15	1829
CRP	0.06 (−0.03, 0.14)	.14	1829
Cystatin C	3057.47 (−929.01, 7043.94)	.11	1829
GDF15	−1.10 (−22.47, 20.27)	.90	1829
Leptin	167.03 (−318.93, 653)	.43	1829
Pack-years	0.14 (−1.97, 2.25)	.88	1829
PAI1	−47.89 (−624.6, 528.82)	.85	1829
TIMP1	98.66 (−25.24, 222.55)	.099	1829

Model estimates are for veterans (nonveterans are the reference group).

Minimally-adjusted model adjustments: chronological age, chronological age², sex, and race/ethnicity.

Fully-adjusted model adjustments: Minimally-adjusted + alcohol, BMI, education, general health, occupation, physical activity, PIR, smoking, and estimated leukocyte proportions. BMI, body mass index; PIR, poverty-to-income ratio.

P < .05: statistically significant.

P < .10: marginally significant.