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Fig. 1. Stereodiagram of the final 2Fo–Fc electron density map for the tetragonal crystal form of IGF2R-Dom11, contoured at 1.7σ. Residues Ile1572 and Phe1567 are in the putative IGF-II binding site (hydrophobic patch 1; see text). A crystal contact molecule is shown as green balls-and-sticks demonstrating the packing of hydrophobic patch 1 against hydrophobic patch 2 (around Ile1627).
