Table 3.
Mean values and standard deviation of QST parameters stratified by Visual Snow, migraine status and corresponding two-way ANOVA p-values for main effects and their interaction
| VSS | Migraine | CDT | WDT | TSL | CPT | HPT | MDT | MPT | MPS | WUR | VDT | PPT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| + | + | -2.13 ± 1.02 | 3.49 ± 2.64 | 4.93 ± 3.01 | 21.05 ± 7.73 | 45.33 ± 2.35 | 0.47 ± 0.34 | 209.51 ± 94.80 | 3.12 ± 2.50 | 2.43 ± 1.09 | 7.44 ± 0.56 | 63.03 ± 14.46 |
| - | -2.07 ± 1.11 | 3.10 ± 2.34 | 5.17 ± 2.91 | 21.92 ± 8.04 | 44.93 ± 3.54 | 0.53 ± 0.35 | 261.46 ± 126.99 | 3.17 ± 4.38 | 2.66 ± 1.00 | 7.30 ± 0.60 | 73.17 ± 17.79 | |
| - | + | -1.64 ± 0.81 | 2.77 ± 1.94 | 4.78 ± 3.06 | 22.28 ± 7.00 | 45.00 ± 2.33 | 0.42 ± 0.17 | 298.24 ± 136.15 | 2.92 ± 3.12 | 2.96 ± 1.41 | 7.30 ± 0.30 | 52.38 ± 10.36 |
| - | -1.63 ± 1.06 | 2.34 ± 1.35 | 3.85 ± 1.79 | 19.98 ± 6.63 | 43.87 ± 3.04 | 0.49 ± 0.30 | 246.10 ± 111.64 | 2.74 ± 2.20 | 2.50 ± 1.08 | 7.51 ± 0.39 | 68.51 ± 20.41 | |
| Two-Way ANOVA: Effect of Visual Snow, Migraine, and Their Interaction (Bonferroni-corrected p-values for 11 comparisons) | ||||||||||||
| Effect of VSS | 0.627 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 0.264 | |
| Effect of Migraine | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 0.088 | |
| Effects of VSS x Migraine | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | |
CDT and WDT are measured in °C relative to baseline; TSL, CPT, and HPT in absolute °C; MDT and MPT in mN; MPS as a score out of 100; WUR is unitless; VDT as a score out of 8; and PPT in N/cm². For ANOVA Analysis, all variables were log transformed, except CPT, HPT and VDT, as described by Rolke et al. [10]. Additionally, CDT and WDT values were multiplied by -1 prior to log transformation so that higher numbers represent higher temperatures thresholds and are reported with positive numbers in the manuscript