Table I. Mutant pacC alleles characterized in this work.
Allele | DNA mutationa | Mutant protein | Change in protein |
---|---|---|---|
pacCΔ8 | [del(1103–1187); del(1410–2179)] | (5–168)::(408–678) | Δ(169–407) |
pacCΔ9 | [del(1103–1187); del(1410–1660); del(1754–2179)] | (5–168)::(235–265)::(408–678) | Δ(169–234, 266–407) |
pacCΔ10 | [del(1103–1187); del(1476–1528); del(1754–2179)] | (5–265)::(408–678) | Δ(266–407) |
pacCΔ11 | [del(1103–1187); del(1476–1528); del(1661–2179)] | (5–234)::(408–678) | Δ(235–407) |
pacCΔ13 | [del(1103–1187); del(1476–1528); del(2393–2464)] | (5–478)::(503–678) | Δ(479–502) |
pacCc15 | 2457ins27 | 5–500 + Ser | A501S; R502stop |
pacC+/–209 | T2451C | Leu498Ser | L498S |
pacC+/–210 | G2452T | Leu498Phe | L498F |
apacC coordinates as in GenBank Z47081 (Tilburn et al., 1995). Nucleotides 1103–1187 and 1476–1528 correspond to INV1 and INV2, respectively.