Table 4. VEGFR-2 kinase inhibitory activity of compounds 4a–4d, 6a–6c, 6f, 6h, 6i and sorafenib.
| Compound ID | VEGFR-2 kinase | Compound ID | VEGFR-2 kinase |
|---|---|---|---|
| IC50 (μM) | IC50 (μM) | ||
| 4a | 1.176 | 6a | 0.189 |
| 4b | 0.319 | 6b | 0.371 |
| 4c | 0.144 | 6c | 0.406 |
| 4d | 0.105 | 6f | 0.172 |
| Sorafenib | 0.081 | 6h | 0.561 |
| 6i | 0.072 |