Table 5. BRAFWT/BRAFV600E kinases inhibitory activity of compound 4c and vemurafenib.
| Compound ID | BRAFWT kinase | BRAFV600E kinase |
|---|---|---|
| IC50 (μM) | ||
| 4c | 0.201 ± 0.006 | 0.101 ± 0.003 |
| Vemurafenib | 0.156 ± 0.005 | 0.063 ± 0.002 |
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