Table 3.

(a) Net reclassification indexes of diverse combination models, (b) Integrated discrimination improvement test of diverse combination models

(a)
Compared models	Basic model	NRI | p value
		Training cohort	Testing cohort
H1 − AP+T2WI +CRH	H1 − AP+T2WI	0.310 | <0.001	0.146 | 0.247
H1 − AP+T2WI +CRH	CRH	0.537 | <0.001	0.348 | 0.059
CRH	Clinical	0.343 | 0.001	0.158 | 0.405
CRH	Radiologic	0.380 | <0.001	0.351 | 0.020
CRH	Habitat	0.138 | 0.042	0.230 | 0.156
H1 − AP+T2WI	H1 − AP	0.101 | 0.174	0.242 | 0.088
H1 − AP+T2WI	H1 − T2WI	0.210 | 0.005	0.230 | 0.156

(b)
Compared models	Basic model	IDI | p value
		Training cohort	Testing cohort
H1 − AP+T2WI +CRH	H1 − AP+T2WI	0.155 | <0.001	0.041| 0.296
H1 − AP+T2WI +CRH	CRH	0.279 | <0.001	0.250 | 0.003
CRH	Clinical	0.104 | <0.001	0.022 | 0.611
CRH	Radiologic	0.080 | 0.001	0.023 | 0.647
CRH	Habitat	0.038| 0.001	0.009| 0.684
H1 − AP+T2WI	H1 − AP	0.029 | 0.284	0.089 | 0.160
H1 − AP+T2WI	H1 − T2WI	0.018 | 0.519	0.112 | 0.050

Abbreviations: CRH, Clinical-Radiologic-Habitat; AP + T2WI + CRH, the fusion model include the radiomics model of total tumor volume in AP and T2WI and clinical, radiologic, habitat features; H_{1 − AP+T2WI} + CRH, the fusion model include the radiomics model of habitat 1 subregion in AP and T2WI and clinical, radiologic, habitat features