Table 2.
GRADEa certainty of patient outcomes in five included studies of the vitamin and mineral requirements in patients > 100 days post-SCT and during GVHD
| Study Design | Certainty Assessment | ||||||
|---|---|---|---|---|---|---|---|
| Risk of Bias | Inconsistency | Indirectness | Imprecision | Publication Bias | Certainty | ||
| Vitamin D | Observational | Serious | Very Serious | Very Serious | Serious | Not suspected | Very Low |
| BMD [22, 23, 28, 32] | |||||||
| Calcium | Observational, RCT | Serious | Not suspected | Very Serious | Very Serious | Not suspected | Very Low |
| BMD [32, 36] | |||||||
| aGRADE = Grading of Recommendations Assessment, Development, and Evaluation | |||||||