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. 2025 Nov 7;33(12):1025. doi: 10.1007/s00520-025-10024-8

Table 2.

GRADEa certainty of patient outcomes in five included studies of the vitamin and mineral requirements in patients > 100 days post-SCT and during GVHD

Study Design Certainty Assessment
Risk of Bias Inconsistency Indirectness Imprecision Publication Bias Certainty
Vitamin D Observational Serious Very Serious Very Serious Serious Not suspected Very Low
BMD [22, 23, 28, 32]
Calcium Observational, RCT Serious Not suspected Very Serious Very Serious Not suspected Very Low
BMD [32, 36]
aGRADE = Grading of Recommendations Assessment, Development, and Evaluation