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Fabrication of CGD TRHs. (A) Synthesis of hydrogel. (B) Proposed molecular mechanisms for CS thermosensitive gelation caused by GlyP and dihydrocaffeic acid, (C) at physiological temperatures (e.g., proton transfer and electrostatic attraction). (D) Images showing the hydrogel gelation precursor solutions at 37 °C [110]. Copyright 2023. Reproduced with permission from Elsevier.
