Table II. Spontaneous reversion frequency at trp1-1 and ade2-1 alleles.
| Reversion frequency/107 viable cells (fold increase) at 30°C | ||
|---|---|---|
| Trp+ | Ade+ | |
| Wild type | 2.0 (×1) | 3.6 (×1) |
| mgs1 | 8.5 (×4.2) | 8.5 (×2.4) |
| rad5 | 13.3 (×6.7) | 13.3 (×3.7) |
|
mgs1 rad5 |
1288.2 (×644) |
1025.1 (×284) |
| Reversion frequency/107 viable cells (fold increase) at 25°C | ||
| Wild type | 1.2 (×1) | 1.5 (×1) |
| mgs1 | 5.9 (×4.9) | 4.3 (×2.8) |
| pol3-13 | 6.3 (×5.3) | 3.2 (×2.1) |
| mgs1 pol3-13 | 43.9 (×36.4) | 13.9 (×9.2) |
The reversion frequency was determined as described in Materials and methods. The data are the averages of five independent measurements.