Fig. 4. The VDR CTE resembles that of TR and is present in solution. (A) Superimposition of VDR, TR and RevErb DBDs. Proteins were aligned using the recognition helix and half-site DNA. The residue at the end of the core region (Met89) is marked, as is the position of Asp97 of VDR and the position of RevErb that would correspond to residue 97. (B) Circular dichroism of free and complexed VDR DBD.