Table 3.
Specific antibiotic use, multiple infections, rare pathogens infections, and specimen type distribution of patients with different results.
| Characteristics | Culture positive mNGS negative (n=14) | Culture negative mNGS positive (n=38) | Culture positive mNGS positive* (n=27) | P-value |
|---|---|---|---|---|
| Use antibiotics before sampling | 4 (28.6%) | 26 (68.4%) | 9 (33.3%) | 0.005* |
| Multiple infections | 2 (14.3%) | 13 (34.2%) | 7 (25.9%) | 0.256 |
| Infections with rare pathogens | 4 (28.6%) | 14 (36.8%) | 6 (22.2%) | 0.445 |
| Joint fluid | 5 (35.7%) | 15 (39.5%) | 8 (29.6%) | 0.716 |
| Intraoperative tissue | 5 (35.7%) | 29 (76.3%) | 12 (44.4%) | 0.006* |
| Prosthesis ultrasound fluid | 6 (42.9%) | 13 (34.2%) | 8 (29.6%) | 0.699 |
*: Patients with both positive tests and non-identical and completely different results.