Table 4.
Distribution of pathogens with inconsistent results between microbial culture and mNGS testing in the PJI and AF groups.
| Pathogen | Culture positive, mNGS negative (n=17) | Culture negative, mNGS positive (n=46) | P-value |
|---|---|---|---|
| Anaerobic bacteria | 1 | 5 | 0.481 |
| Gram-negative bacilli | 2 | 6 | 0.631 |
| Candida | 1 | 1 | 0.470 |
| Coagulase-negative staphylococci | 8 | 5 | 0.004 |
| Streptococcus | 0 | 9 | 0.047 |
| Mycobacterium tuberculosis | 0 | 2 | 0.530 |
| Staphylococcus aureus | 1 | 3 | 0.707 |
| Pseudomonas | 1 | 2 | 0.618 |
| Mycoplasma | 0 | 9 | 0.047 |
| Non-tuberculous mycobacteria | 1 | 3 | 0.707 |
| Other | 2 | 1 | 0.175 |