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. 2025 Nov 10;22:135. doi: 10.1186/s12986-025-01036-6

Table 3.

Odds ratios for the effect of change in UPF consumption and baseline UPF consumption on prediabetes/type 2 diabetes, impaired fasting glucose, and impaired glucose tolerance

OR (95% CI)
UPF%Inline graphic1 UPF% at baseline 2
All participants (n = 85)
Prediabetes/T2D 1.51 (1.04, 2.31) 1.41 (0.90, 2.26)
IFG 1.21 (0.83, 1.79) 1.22 (0.71, 2.05)
IGT 2.58 (1.43, 5.85) 1.31 (0.65, 2.69)
Excluding participants with Prediabetes/T2D at baseline (n= 61)
Prediabetes/T2D 1.56 (1.00, 2.59) 1.54 (0.93, 2.64)
IFG 1.24 (0.74, 2.08) 1.67 (0.86, 3.40)
IGT 2.30 (1.28, 5.01) 1.42 (0.67, 3.12)

*All outcomes were measured at the follow-up visit. Effects are scaled by 10 units

1Models were adjusted for age, sex, ethnicity, exercise at follow-up, total energy intake at follow-up, and UPF% at baseline

2Models were adjusted for age, sex, ethnicity, exercise at follow-up, total energy intake at follow-up, and UPF%Δ

**Abbreviations: UPF%: percent of diet from ultra-processed foods; UPF%Δ: change in percent of diet from ultra-processed foods between visits; T2D: type 2 diabetes; IFG: impaired fasting glucose; IGT: impaired glucose tolerance