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. 2025 Oct 29;16:1702549. doi: 10.3389/fimmu.2025.1702549

Table 3.

Linear mixed model results, where group represents electrode grouping (basal, middle, apical), Sequence represents implant sequence (first implant, second implant), Age represents age grouping as a binary variable (< 18 years, > 18 years), and time is time since baseline visit in months.

Variable Estimate SE df t-value p-value
Intercept − 520.59 208.61 4,479 − 2.50 0.0126
Group (mid) − 108.96 129.85 4,479 − 0.84 0.4014
Group (apical) − 906.97 129.99 4,479 − 6.98 < 0.0001
Sequence (second) 820.28 140.76 4,479 5.83 < 0.0001
Age (< 18) − 497.37 232.11 4,479 − 2.14 0.0322
Log (time) 414.47 64.16 4,479 6.46 < 0.0001
Group (mid) * sequence − 205.02 137.41 4,479 − 1.49 0.1358
Group (apical) * sequence 25.82 137.55 4,479 0.19 0.8511
Sequence * log (time) − 160.36 37.19 4,479 − 4.31 < 0.0001
Group (mid) * log (time) − 125.01 35.93 4,479 − 3.48 0.0005
Group (apical) * log (time) − 174.57 35.93 4,479 − 4.86 < 0.0001

SE, standard error; df, degrees of freedom.