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. 2025 Oct 29;16:1612379. doi: 10.3389/fneur.2025.1612379

Table 2.

Cerebral perfusion in each white matter region.

Index Perfusion mL/(min*100 g) t P
Mild to moderate Severe
Brachium pontis_corr-CBF 40.61 ± 7.57 39.79 ± 6.23 0.514 0.608
Fasciculus crossed pontis_corr-CBF 47.17 ± 10.58 44.88 ± 9.25 0.983 0.328
Knee of the corpus callosum_corr-CBF 33.84 ± 3.96 33.10 ± 6.30 0.536 0.593
Corpus callosum body_corr-CBF 35.84 ± 6.34 31.73 ± 8.60 2.121 0.037
Corporis callosi splenium_corr-CBF 34.85 ± 7.95 32.73 ± 8.45 1.060 0.292
Fornix corr-CBF 40.59 ± 8.83 34.28 ± 7.12 3.430 0.001
Corticospinal tract (R)corr-CBF 44.26 ± 9.57 41.86 ± 7.91 1.185 0.239
Corticospinal tract (L) corr-CBF 42.86 ± 7.59 41.31 ± 7.20 0.878 0.382
Lemniscus medialis (R) corr-CBF 41.54 ± 11.30 39.75 ± 8.73 0.781 0.437
Lemniscus medialis (L)corr-CBF 42.76 ± 11.17 41.00 ± 15.38 0.510 0.611
Corpora restiformia(R)_corr-CBF 43.60 ± 9.39 43.59 ± 16.66 0.004 0.997
Corpora restiformia(L)_corr-CBF 43.82 ± 8.10 41.75 ± 9.75 0.918 0.361
Pedunculus cerebellaris superior (R)_corr-CBF 41.34 ± 8.41 41.92 ± 10.48 −0.244 0.808
Pedunculus cerebellaris superior(L)_corr-CBF 40.78 ± 8.12 41.03 ± 11.30 −0.097 0.923
Pedunculus cerebri_(R)_corr-CBF 40.98 ± 6.03 40.70 ± 7.82 0.157 0.876
Pedunculus cerebri (L)_corr-CBF 40.54 ± 7.23 40.55 ± 5.93 −0.003 0.998
Anterior limb of internal capsule_(R)_corr-CBF 38.84 ± 5.94 40.89 ± 6.69 −1.312 0.193
Anterior limb of internal capsule_(L)_corr-CBF 41.27 ± 6.88 41.30 ± 6.59 −0.017 0.986
Posterior limb of internal capsule_(R)_corr-CBF 34.58 ± 5.50 36.25 ± 6.84 −1.065 0.290
Posterior limb of internal capsule_(L)_corr-CBF 34.34 ± 5.17 36.94 ± 6.20 −1.821 0.072
Posterior lens of internal capsule_(R)_corr-CBF 35.34 ± 6.52 36.48 ± 8.01 −0.620 0.537
Posterior lens of internal capsule_(L)_corr-CBF 37.79 ± 7.59 37.95 ± 8.07 −0.082 0.935
Anterior radiation crown_(R)_corr-CBF 29.21 ± 3.53 30.37 ± 6.28 −0.849 0.399
Anterior radiation crown_(L)_corr-CBF 30.21 ± 4.51 30.18 ± 6.55 0.022 0.982
Upper radiation crown_(R)_corr-CBF 27.45 ± 3.92 27.58 ± 6.46 −0.090 0.928
Upper radiation crown_(L)_corr-CBF 28.17 ± 4.18 27.95 ± 6.09 0.162 0.872
Posterior radiation crown_(R)_corr-CBF 26.88 ± 5.26 26.22 ± 6.81 0.428 0.669
Posterior radiation crown_(L)_corr-CBF 27.08 ± 4.79 26.25 ± 6.32 0.581 0.563
Posterior thalamic radiation (Including apparent radiation)_(R)_corr-CBF 27.48 ± 6.16 26.46 ± 8.48 0.533 0.595
Posterior thalamic radiation (Including apparent radiation)__(L)_corr-CBF 27.29 ± 5.69 26.63 ± 8.79 0.338 0.736
Sagittal layer (including inferior longitudinal fasciculus and inferior fronto-occipital fasciculus)(R)_corr-CBF 35.22 ± 5.90 34.17 ± 7.11 0.641 0.523
Sagittal layer (including inferior longitudinal fasciculus and inferior fronto-occipital fasciculus)__(L)_corr-CBF 37.03 ± 7.32 35.05 ± 6.72 1.187 0.238
Capsula externa_(R)_corr-CBF 38.69 ± 6.41 39.25 ± 7.06 −0.335 0.738
Capsula externa_(L)_corr-CBF 40.76 ± 7.47 39.23 ± 6.38 0.950 0.345
Cingulate gyrus_(R)corr-CBF 46.65 ± 9.73 43.23 ± 9.56 1.476 0.144
Cingulate gyrus (L)_corr-CBF 46.19 ± 8.84 42.96 ± 8.69 1.533 0.129
Cingulate (hippocampus) (R)_corr-CBF 45.77 ± 8.31 44.90 ± 8.33 0.433 0.666
Cingulate (hippocampus) (L)_corr-CBF 45.76 ± 8.42 45.46 ± 6.93 0.169 0.866
Fornix/striae terminalis_(R)_corr-CBF 45.25 ± 8.93 41.17 ± 8.38 1.987 0.050
Fornix/striae terminalis (L)_corr-CBF 44.23 ± 9.67 42.14 ± 8.47 0.984 0.328
Fasciculus arcuatus (R)corr-CBF 34.98 ± 7.78 34.07 ± 7.49 0.502 0.617
Fasciculus arcuatus (L)_corr-CBF 36.00 ± 7.86 33.97 ± 6.82 1.183 0.240
Fasciculus fronto-occipitalis supratica _(R)_corr-CBF 29.86 ± 5.84 32.10 ± 5.99 −1.560 0.122
Fasciculus fronto-occipitalis supratica (L)_corr-CBF 31.80 ± 5.05 31.86 ± 5.99 −0.042 0.966
Unciform fasciculus (R)_corr-CBF 32.54 ± 5.68 34.74 ± 7.53 −1.294 0.199
Unciform fasciculus_(L)_corr-CBF 34.17 ± 5.65 34.87 ± 6.14 −0.482 0.631
Tapetum_(R)_corr-CBF 24.38 ± 5.47 22.94 ± 8.78 0.743 0.459
Tapetum_(L)_corr-CBF 23.20 ± 5.20 22.99 ± 8.97 0.106 0.916