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. 2025 Oct 29;14(10):7438–7449. doi: 10.21037/tcr-2025-1944

Table 2. Indications and monitoring items for anticoagulant drug monitoring.

Anticoagulant drugs Monitoring indicators Monitoring items
UFH Routine monitoring aPTT or anti-Xa (aPTT exceeds the upper limit of normal or is >1.5 times the patient’s baseline value)
LMWH Severe renal impairment, cancer patients with venous thrombosis, bleeding Anti-Xa
DOACs Bleeding, PARPi treatment Anti-Xa

Anti-Xa, anti-factor Xa; aPTT, activated partial thromboplastin time; DOACs, direct oral anticoagulants; LMWH, low-molecular- weight heparin; UFH, unfractionated heparin.