Fig. 7. Cyclosporin inhibits PRRIV activity. (A) EL4 cells were transfected with 10 µg of PRRIVWT construct. Transfected cells were incubated with medium, CsA, PI or PI + CsA. (B) EL4 cells were transfected with 10 µg of WT-PRRIVWT construct. Transfected cells were incubated with medium, CsA, PI or PI + CsA. (C) EL4 cells were transfected with 10 µg of NFATm-PRRIVm6 construct, which has mutant NFAT sites both upstream and in PRRIV. Transfected cells were incubated with medium, CsA, PI or PI + CsA.