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. 2025 Nov 5;26(21):10736. doi: 10.3390/ijms262110736
131I Iodine-131
177Lu Lutetium-177
18F Fluorine-18
18F-FAMT 18F-L-3-fluoro-α-methyl-tyrosine
18F-FBPA 18F-fluoro-boronophenylalanine
[18F]FSPG (4S)-4-(3-fluoropropyl)-L-glutamate
211At Astatine-211
213Bi Bismuth-213
223Ra Radium-223
225Ac Actinium-225
AA Amino acid
AAMP 2-[211At]AAMP (LAT1-targeted analogue)
AAMT 211At-labeled α-methyl-L-tyrosine
ABCB1 ATP-binding cassette subfamily B member 1 (P-glycoprotein)
ABCG2 ATP-binding cassette subfamily G member 2 (BCRP)
ADC Antibody–drug conjugate
ADCC Antibody-dependent cellular cytotoxicity
AHR Aryl hydrocarbon receptor
AKT Protein kinase B
ALK Anaplastic lymphoma kinase
ASCT2 Alanine-serine-cysteine transporter 2 (SLC1A5)
ATF4 Activating transcription factor 4
ATR Ataxia telangiectasia and Rad3-related protein
B2M Beta-2-microglobulin
BCH 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid
BenSer Benzylserine
CD98hc/4F2hc Heavy chain of CD98 (SLC3A2)
CDC Complement-dependent cytotoxicity
CHK1 Checkpoint kinase 1
CSC Cancer stem cell
CYP Cytochrome P450
DDR DNA damage response
DM1 Maytansinoid DM1
DNA Deoxyribonucleic acid
DSB(s) Double-strand break(s)
DTP Drug-tolerant persister(s)
EBRT External-beam radiotherapy
EGFR Epidermal growth factor receptor
EMT Epithelial–mesenchymal transition
ERBB3 Erb-B2 receptor tyrosine kinase 3 (HER3)
ERK Extracellular signal-regulated kinase
EZH2 Enhancer of zeste homolog 2
F(ab′)2 Antibody fragment F(ab′)2
FIN(s) Ferroptosis inducer(s)
GPX4 Glutathione peroxidase 4
GMP Good Manufacturing Practice
GSH Glutathione
GATOR2 GAP activity toward Rags complex 2
HIF-1 Hypoxia-inducible factor 1
HIF-2α Hypoxia-inducible factor 2 alpha
HLA-I Human leukocyte antigen class I
HMGB1 High mobility group box 1
HR Homologous recombination
ICI(s) Immune checkpoint inhibitor(s)
ICD Immunogenic cell death
IDO1 Indoleamine 2,3-dioxygenase 1
IEDDA Inverse electron-demand Diels–Alder reaction
iRGD Internalizing the RGD peptide
JPH203 Nanvuranlat (LAT1 inhibitor)
KEAP1 Kelch-like ECH-associated protein 1
KRASG12C KRAS p.G12C mutation
LAG-3 Lymphocyte-activation gene 3
LAT1 L-type amino acid transporter 1 (SLC7A5)
LET Linear energy transfer
MABG meta-Astatobenzylguanidine
MAPK Mitogen-activated protein kinase
mAb Monoclonal antibody
mCRPC Metastatic castration-resistant prostate cancer
MeV Mega-electron volt
MDSC(s) Myeloid-derived suppressor cell(s)
MMAE Monomethyl auristatin E
mTOR Mechanistic target of rapamycin
mTORC1 mTOR complex 1
NaAt Sodium astatide ([211At]NaAt)
NAD(P)H Nicotinamide adenine dinucleotide (phosphate), reduced form
NFE2L2 Nuclear factor erythroid-derived 2-like 2
NHEJ Non-homologous end-joining
NRF2 Nuclear factor erythroid 2-related factor 2
NSCLC Non-small cell lung cancer
OER Oxygen-enhancement ratio
OS Overall survival
PD-L1 Programmed death-ligand 1
PEG Polyethylene glycol
PET Positron emission tomography
PI3K Phosphoinositide 3-kinase
PK Pharmacokinetics
PLGA Poly(lactic-co-glycolic acid)
PBD Pyrrolobenzodiazepine
PRIT Pretargeted radioimmunotherapy
PSMA Prostate-specific membrane antigen
Rag GTPases Ras-related GTP-binding proteins A–D
RGD Arg-Gly-Asp peptide
ROS Reactive oxygen species
ROS1 c-ros oncogene 1 (receptor tyrosine kinase)
RT Radiotherapy
SAB N-succinimidyl astatobenzoate
SAGMB Guanidinomethyl-substituted succinimidyl astatobenzoate
SBRT Stereotactic body radiotherapy
SLC1A5 Solute carrier family one member 5 (ASCT2)
SLC3A2 Solute carrier family three member 2 (CD98hc/4F2hc)
SLC7A5 Solute carrier family seven member 5 (LAT1)
SLC7A11 Solute carrier family seven member 11 (xCT)
SLC38A2 (SNAT2) Sodium-coupled neutral amino acid transporter 2
SLC43A2 Solute carrier family 43 member 2
SNAT2 See SLC38A2
TAZ WW domain-containing transcription regulator 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TIM-3 T cell immunoglobulin and mucin domain 3
TKI(s) Tyrosine kinase inhibitor(s)
TME Tumor microenvironment
Treg(s) Regulatory T cell(s)
TRT Targeted radionuclide therapy
V-9302 Small-molecule glutamine transport inhibitor
VISTA V-domain Ig suppressor of T-cell activation
WEE1 WEE1 G2 checkpoint kinase
xCT Cystine/glutamate antiporter (SLC7A11)
YAP Yes-associated protein