Skip to main content
. 2025 Oct 22;30(21):4149. doi: 10.3390/molecules30214149
ACN Acetonitrile
ADMET Absorption, distribution, metabolism, excretion, and toxicity
AMES The name of the test used in mutagenicity assessment
ATCC American Type Culture Collection
BBB Blood–brain barrier
BCRJ Rio de Janeiro Cell Bank
Caco2 Human colorectal adenocarcinoma cells
CC50 50% Cytotoxic Concentration
CL Clearance capacity
CNS Central nervous system
CPE Cytopathic effect
CYP450 Cytochrome P450
DENV Dengue Virus
DMEM Dulbecco’s Modified Eagle Medium
DMSO Dimethyl Sulfoxide
EC50 50% Effective Concentration
FBS Fetal bovine serum
GC-MS Gas chromatography-mass spectrometry
hERG Human ether-go-go gene
HIV Human Immunodeficiency Virus
ICTV International Committee on Taxonomy of Virus
IFN-α-2a Human recombinant interferon alfa-2a
LD50 Lethal Dose for 50%.
LOAEL Lowest observed adverse effect level
LogP Logarithm of the partition coefficient
M.O.I Multiplicity of infection
MRTD Maximum recommended therapeutic dose
MTT (3-(4,5-Dimetil-2-tiazolyl)-2,5-Difeniltetrazólio)
MVDA Multivariate data analysis
NPX Narciclasine-4-O-β-D-xylopyranoside
NS Non-structural
OCT2 Renal organic cation transporter 2
RO5 Lipinski’s Rule of Five
RT Retention time
RVFV Rift Valley Fever Virus
SARS Severe acute respiratory syndrome
SISGEN National System of Genetic Heritage Management
SMILES Simplified Molecular Input Line Entry System
TMEM41B Transmembrane Protein 41B
TRIM56 Tripartite Motif Containing 56
UHPLC Ultra-high-performance liquid chromatograph
VDss Volume of distribution at steady state
wt-YFV Wild-type yellow fever virus
YF Yellow fever
YFV Yellow Fever Virus
ZIKV Zika Virus
γ-PGA polymer poly-γ-glutamic acid