| TNF-α | tumor necrosis factor-alpha |
| IL | interleukin |
| IGF-1 | insulin-like growth factor 1 |
| PI3K | phosphatidylinositol 3-kinase |
| Akt | protein kinase B |
| mTOR | mammalian target of rapamycin |
| ROS | reactive oxygen species |
| NF-κB | nuclear factor kappa B |
| FoxO3a | forkhead box O3a (FoxO3a) |
| RCE | Rosa canina extract |
| p-PI3K | phosphorylated-PI3K |
| p-Akt | phosphorylated-Akt |
| p-mTOR | phosphorylated-mTOR |
| p70S6K | 70-kDa ribosomal S6 kinase |
| p-p70S6K | phosphorylated-p70S6K |
| 4EBP1 | 4E-binding protein 1 |
| p-4EBP1 | phosphorylated-4EBP1 |
| DMEM | Dulbecco’s modified Eagle’s medium |
| FBS | fetal bovine serum |
| CON | mice received no surgery and were supplemented with saline |
| IMM | mice received immobilization surgery and were supplemented with saline |
| RCL | mice received immobilization surgery and were orally administered RCE at 200 mg/kg/day |
| RCH | mice received immobilization surgery and were orally administered RCE at 400 mg/kg/day |
| GA | gastrocnemius |
| SOL | soleus |
| TA | tibialis anterior |
| EDL | extensor digitorum longus |
| H&E | hematoxylin & eosin |
| ELISA | Enzyme-linked immunosorbent assay |
| RT-PCR | Reverse transcription-polymerase chain reaction |
| SDS-PAGE | sulfate-polyacrylamide gel electrophoresis |
| TBS-T | Tris-buffered saline containing 0.1% Tween 20 |
| ECL | enhanced chemiluminescence |
| SEM | standard error of the mean |
| ANOVA | one-way analysis of variance |
| SOD | superoxide dismutase |
| GPX | glutathione peroxidase |
| MTT | thiazolyl blue tetrazolium bromide |
| MyoD | myogenic differentiation 1 |
| MHC | myosin heavy chain |
| MuRF1 | muscle ring finger 1 |
| Atrogin-1 | muscle atrophy F-box |
| CSA | cross-sectional area |