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. 2025 Nov 1;17(21):3538. doi: 10.3390/cancers17213538
CDK4/6i CDK4/6 inhibitors
ET Endocrine therapy
DRFS Distant recurrence-free survival
iDFS Invasive disease-free survival
OS Overall survival
HR+ Hormone Receptor-positive
HER2− Human Epidermal Growth Factor 2-negative
RCTs Randomized controlled trials
CDKs Cyclin-dependent kinases
ER+ Estrogen receptor positive
Rb Retinoblastoma protein
a/mBC Advanced or metastatic breast cancer
PFS Progression-free survival
ABC Advanced breast cancer
DFS Disease-free survival
HR Hazard ratios