Table I. Frequency of proviral integrations near common activated genes in MuLV-induced lymphomas.
Genotype | Oncogene activation (%) |
|||
---|---|---|---|---|
Myc | Pim1 | Gfi1 | Cyclin D2 | |
WT (n = 38) | 32 | 21 | 26 | 3 |
p21–/– (n = 41) | 32 | 29 | 26 | 5 |
p21–/–; p27+/– (n = 58) | 53 | 17 | 29 | 4 |
p27–/– (n = 37) | 74 | 11 | 29 | 0 |
p21–/–; p27–/– (n = 40) | 69 | 10.5 | 32 | 0 |