Table 2.

Multivariable logistic regression analysis of FS risk factors

Predictor	aOR	95% CI	P-value	Variance Explained (Partial R²)
Age < 1 year	3.5	1.8–6.8	< 0.001	0.18
Male sex	1.8	1.1–2.9	0.016	0.06
Unvaccinated	3.2	1.8–5.7	< 0.001	0.22
IL-6 > 10 pg/mL	2.8	1.3–6.1	0.006	0.12
D-dimer > 0.5 mg/L	2.1	1.2–3.7	0.016	0.08
Omicron infection	2.2	1.2–4.0	0.01	0.10
Model Summary				Nagelkerke R²=0.42

Adjusted for age, sex, comorbidities, and therapies

Partial R² denotes the proportion of variance in febrile seizure risk uniquely explained by each predictor after adjusting for covariates

Model Fit: AIC=392.74, Nagelkerke R²=0.42,Hosmer-Lemeshow χ²=7.84, df=8, P=0.45

CI Confidence Interval

All P-values reported remained significant after Bonferroni correction for multiple comparisons (α = 0.01)