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. 2025 Nov 13;25:929. doi: 10.1186/s12887-025-06095-5

Table 3.

Biomarker profiles stratified by seizure recurrence

Biomarker Single Seizure (n = 75) Recurrent Seizures (n = 27) Median Difference (95% CI) P-value
IL-6 (pg/mL) 8.2 [5.1–12.1] 15.6 [10.3–21.4] 7.4 (4.2–10.6) 0.001
D-dimer (mg/L) 0.9 [0.6–1.3] 1.3 [0.7–1.9] 0.4 (0.2–0.6) 0.02
CRP (mg/L) 8.5 [4.2–12.2] 9.3 [5.1–13.4] 0.8 (− 0.5–2.1) 0.15

Differences calculated using the Hodges-Lehmann estimator

IQR Interquartile Range