. 2025 Nov 12;26:627. doi: 10.1186/s12882-025-04562-w

Table 2.

Platelet characteristics stratified by platelet slope pattern after CRRT initiation

	Overall (n = 2226)	Descending (n = 655)	Stable (n = 1297)	Ascending (n = 274)	p
Platelet count at CRRT initiation (10³/µL)	158.9 [101.8, 238.7]	235.0 [171.9, 327.5]	129.6 [81.3, 192.7]	153.8 [101.0, 221.4]	< 0.001
Highest platelet count after CRRT initiation (10³/µL)	176.5 [112.5, 267.4]	232.6 [161.0, 327.2]	134.1 [87.7, 201.1]	287.6 [210.1, 386.4]	< 0.001
Lowest platelet count after CRRT initiation (10³/µL)	92.3 [45.6, 155.4]	101.0 [51.3, 167.5]	79.9 [38.6, 137.9]	139.7 [84.9, 206.3]	< 0.001
Slope of platelet before CRRT initiation (10³/µL/day)	-8.8 [-16.5, -0.1]	-4.5 [-12.8, 7.0]	-10.7 [-17.3, -2.4]	-10.4 [-19.6, -1.9]	< 0.001
Slope of platelet after CRRT initiation (10³/µL/day)	-4.1 [-12.1, 2.4]	-18.3 [-26.8, -13.7]	-2.3 [-5.6, 1.7]	18.5 [13.2, 27.1]	< 0.001

Overall
(n = 2226)

Descending
(n = 655)

Stable
(n = 1297)

Ascending
(n = 274)

Platelet count at CRRT initiation

(10³/µL)

158.9

[101.8, 238.7]

235.0

[171.9, 327.5]

129.6

[81.3, 192.7]

153.8

[101.0, 221.4]

< 0.001

Highest platelet count after CRRT initiation (10³/µL)

176.5

[112.5, 267.4]

232.6

[161.0, 327.2]

134.1

[87.7, 201.1]

287.6

[210.1, 386.4]

< 0.001

Lowest platelet count after CRRT initiation (10³/µL)

92.3

[45.6, 155.4]

101.0

[51.3, 167.5]

79.9

[38.6, 137.9]

139.7

[84.9, 206.3]

< 0.001

Slope of platelet before CRRT initiation (10³/µL/day)

-8.8

[-16.5, -0.1]

-4.5

[-12.8, 7.0]

-10.7

[-17.3, -2.4]

-10.4

[-19.6, -1.9]

< 0.001

Slope of platelet after CRRT initiation (10³/µL/day)

-4.1

[-12.1, 2.4]

-18.3

[-26.8, -13.7]

-2.3

[-5.6, 1.7]

18.5

[13.2, 27.1]

< 0.001

Abbreviation: CRRT, continuous renal replacement therapy

Numerical variables are presented as median [IQR]